产品目录

分子量：Approximately 12.0kDa,a single non-glycosylated polypeptide chain containing 106 amino acids,which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
储存条件：冷冻（-20℃）

概述

Trefoil factor 2 encoded by the TFF2 gene in humans,belongs to the trefoil factor family that consists of three members named TFF1,TFF2 and TFF3.They are characterized by having at least one copy of the trefoil motif,a 40-amino acid domain that contains three conserved disulfides.The TFFs are stable secretory proteins expressed highly in the gastrointestinal tract(gastric mucosa).TFF2 can inhibit gastrointestinal motility and gastric acid secretion.Additionally,it functions as a structural component of gastric mucus,possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观	Sterile Filtered White lyophilized(freeze-dried)powder.
纯度	＞97%by SDS-PAGE and HPLC analyses.
来源	Escherichia coli.
生物活性	Fully biologically active when compared to standard.The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10ng/ml,corresponding to a specific activity of>1.0×105 IU/mg.
成分	Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,130 mM NaCl.
内毒素	Less than 1 EU/μg of rHuTFF2 as determined by LAL method.
复溶	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20 ℃.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列	EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY

相关搜索：重组人TFF2，TFF2, Human，Recombinant Human Trefoil Factor 2